Ref15P16 - Siliphos® counteracts hepatotoxic effects

Biochemical Pharmacology, Vol. 43, No. 10, pp 2111-2115, (1992)

Lipid Peroxidation and Irreversible Damage in the Rat Hepatocyte Model

Protection by The silybin-phosopholipid Complex IdB 1016

Rita Carini, Adriana Comoglio, Emanuele Albano and Giuseppe Poli*

Department of Experimental Medicine and Oncology, University of Turin, CNR Centre of Immunogenetics and Experimental Oncology, Corso Raffaello 30, Torino, Italy

Abstract-IdB 1016 (Siliphos®) is a new silybin-phospholipid complex which is more bioavailable than the flavonoid silybin itself and displays free radical scavenging and antioxidant properties in liver microsomes. IdB 1016 (Siliphos®) at the concentration which completely prevented MDA formation also protected isolated hepatocytes against toxicity. Similar protection was also obtained in hepatocytes prepared in vivo with IdB 1016 (Siliphos®) while rat supplementation with pure silybin was totally inefficient. These results indicate IdB 1016 (Siliphos®) as being a potentially useful protective agent against free radical-mediated toxic liver injury.

Moreover, it was demonstrated here for the first time that IdB 1016 (Siliphos®) can counteract the hepatotoxic effect of several different compounds acting through oxidative mechanisms, indicating the potential usefulness of the compound as a hepatoprotective agent.

This product seemingly has kept my hep c from progressing out of stage 1. I am very grateful to my dr. for telling me about this product. I have had nothing but excellent service from natural wellness company. I would like to thank you at this time for many years of great customer service.

Joy

I had NAFLD (20% of surface covered with fat) and a few lifestyle changes, some exercise and taking UltraThistle for 6 months - my latest check up revealed that the NAFLD has gone and my liver is functioning normally!!

Steve Claxton

Working good so far, trying to improve liver function of my fiance who is a heavy drinker. Dr. Said to keep taking it and after 3 months of using regular 'NatureMade' milk thistle and a month of 'Ultra Thistle' his liver #'s were back in the normal range.

R. Thompson

I have to thank you and point out to others on the fence about putting their Liver Disease self-treatment on auto-ship for the rest of your life.....I am a long-time NAFLD patient and recently had to do something different because no matter what we do, this is a progressive disease. The products from Natural Wellness came and I received the immediate turn-around I was looking for and even though I am an old lady on low income, I had to decide this was the best choice for my life and the auto-ship idea is a Godsend. I had been taking Milkweed power capsules which stopped working. This new approach is terrific. Thank you Natural Wellness.

Ariel Gail MacLean

I had been drinking far too regularly (5 nights a week), exercising a few times a week and eating less than healthily. I had been taking a CVS brand of Milk Thistle thinking it would protect me. Wrong. Went to the Dr for a pain in my upper-right abs and my liver values (not surprisingly) were moderately elevated to AST/ALT 45/50. I freaked out, did a ton of research, and bought UltraThistle. Along with eating slightly better, only drinking on the weekends (2 nights), and busting my ass in the gym, a month later my liver values have decreased to 26/25. Obviously, my change in lifestyle helped, but about a week after I started taking this, the pain in my upper-right abs has gone away completely. I'd say this stuff works.

I am 59 yrs old & I have been using Ultra Thistle for about 4 months now due to an enlarged liver infused with fat that was making me very sick. The doctor said I may not be able to reverse it. My condition is technically called NASH. My liver is shrinking & I feel so much better. The doctor said I was doing amazing that he had only seen maybe 2 other patients in his entire career turn it around as quickly as I have. He said keep taking it & of course I have a strict diet too. My prognosis was doom & gloom & now I am reversing my NASH! I believe Ultra Thistle is my life saver & I will always take it.

S. Osburn, Missouri

I have used UltraThistle for years with great results. ANY research at all regsrding Milk Thistle will reveal its curative qualities. And of ALL the M.T. out there, Natural Welness' UltraThistle is hands-down the best - specifically in bioavailability. As an aside, my FibroSure numbers remain within specs while using UltraThistle. No taste, no belch, no ill effects - just a squeaky-clean liver! And the service from Natural Wellness has been superb. I'm no healthcare provider; however, I highll recommend BOTH & am in no way connected to either.

Anonymous
Payment Processing